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Chapter 3

“Nutritionals” Used On
The Road Back Program

In 1999, we were assisting individuals off their medication without using nutritional supplements by having people gradually reduce the dosage. We came up with a slow tapering process, wherein the drug was only tapered further when a person felt they could handle the withdrawal side effects caused by the previous taper of the medication. Roughly 50% of the people could taper off their medication using a gradual taper, but the 50% that successfully got off their medication still suffered extreme withdrawal side effects. The F.D.A. and the drug companies now recommend what we were doing in 1999, with a gradual reduction.

However, we were not satisfied with a 50% success rate or with the suffering that still took place during the taper process for the lucky half that could get off their medication. We began experimenting with a few nutritional supplements in 2001 to see if they would help with the side effects, and the success rate increased enough for further investigation.

In 2004 I started a DNA testing company and we conducted hundreds of DNA test on individuals who were either currently taking medication, off their medication already or had never used a psychoactive medication.

We looked at how our individual DNA altered the metabolism of drugs as well as how we were able to metabolize food groups and specific nutrients. This information made it very clear why some people experienced adverse reactions to their drug immediately and why some were able to take the drug for an extended period of time before having a negative reaction. However, the DNA Drug Reaction Test did not give evidence or become useful with how to get a person off a drug. The DNA testing of food groups and nutrients did show promise. With this information, we began to create nutritional formulations in the hope it would help eliminate withdrawal side effects or at the least reduce them to a livable amount.

Although the steps above were complicated to a degree, the real work was to create formulations of supplements that would not interact with drugs and would reduce or eliminate side effects associated with tapering off psychoactive medication. At the time, this was unchartered territory in the scientific community, but with our research and success we now see our discoveries and breakthroughs used by many physicians and drug detoxification programs throughout the world.

The nutritional supplements used with The Road Back Program have changed over the past decade as new discoveries have become known. The spring of 2013, has brought the next generation of research to application. Over the past decade, I have spent thousands of hours researching the correct and most basic nutrient system for this program. This edition of the book makes the program even more effective, easier to follow and dramatically reduces the time it takes to get off psychoactive medications. Our goal is and always will be to get a person feeling better faster and allow an individual to safely reduce their medication in less time.

The breakthrough this spring 2013, deals with the time release medications, benzodiazepines and antipsychotic medications. Most new antidepressants are only available as a time release and antipsychotic medications are quickly following suit. The time release drug could not be reduced slow enough to reduce the risk of withdrawal side effects. Often, the individual would need to go back up on the dosage and would never attempt to taper the drug again, even with encouragement from the prescribing physician to reduce the medication.

When the body’s chemistry or systems are altered, the body will fight back to balance out the attack. Bringing back that balance is critical if a person is taking a psychoactive medication or if they are suffering from the feeling of anxiety, stress or depression without ever having taken a psychoactive drug.

This program is based on clinical studies conducted by major universities and scientific bodies kept in high regard by the medical community. Here are a few of the results of clinical studies used while developing this program: Antidepressants cause insulin resistance, and if you are predisposed to diabetes and take an antidepressant, you have a four-fold increased chance of becoming a diabetic. Prolonged use of benzodiazepines depletes the body of the B vitamin biotin and can cause problems with receptors used by a benzodiazepine. These two examples give an indication of how one might treat medication side effects and why a few supplements are part of this program.

In other words, if you have taken a benzodiazepine for an extended period of time and have depression and/or tingling or numbness of the extremities, you are probably deficient in biotin. Thus, adding biotin to your daily routine will usually handle the symptom if the biotin deficiency is, in fact, the cause.

The list of symptoms associated with insulin resistance is quite long. Diabetes and obesity are two of several conditions resulting from insulin resistance, but there are other symptoms a person will begin experiencing before the onset of such conditions. Antidepressants cause these body conditions and consequently create physical symptoms that can be confused with actual drug withdrawal symptoms, making the withdrawal from any drug more confusing for the individual and their physician.

How the Program Works

Your body naturally triggers a self-protective inflammatory process when a psychoactive medication is started.  This  natural function also responds  to normal activities, such as exercise, fighting off toxins, allergies, illness, incorrect foods, weight gain, medications, you name it.

For example, let’s take a sore throat or an infected cut. The area becomes red and inflamed as the body rushes microscopic “fire fighters” to the area to contain and put out the fire and start the healing process.

However, if your body gets overloaded and can no longer control the inflammation or lacks enough “fire fighters” to douse the flames, then an internal switch flips, and your systems will start going awry, ultimately resulting in an overall imbalance. At this point, but probably earlier in the process, a gene called JNK that is found in all of our cells becomes over activated. If you are taking a drug, there is no doubt the JNK gene is now over activated. This over activation of the JNK gene is the underlying cause of side effects and bodily and mental symptoms associated with all psychoactive drugs.

If you have a physical condition, including menopause, weight gain, diabetes or so many others, and then throw psychoactive medications on top, you can be adding fuel to an already burning fire. In essence, you flip the switch that overloads your body so it can no longer function as intended.

However, and a big however, using supplements (specifically antioxidants) incorrectly, in the wrong amount, combination or time of day, can cause more harm than help.

Reducing the over activation of the JNK gene and cleaning up the cause/effect phenomena is what gives you relief from the drug side effects, allowing the body to heal itself.

The body will produce and release substances called cytokines when the immune system is activated. When the JNK gene becomes over activated, the immune system will begin to have difficulty handling the body and a protein called Interleukin-2 will either plummet or shoot sky high. High Interleukin-2 levels will create a mania in an individual. A chronic high Interleukin-2 will also cause a different substance called Interleukin-6 to become high, and a high level of Interleukin-6 is associated with depression. It is now known, high Interleukin-6 precedes depressions. Here you have the bipolar individual who cycles between mania and depression.

Depending on your body and what you were exposed to, these cytokines may have been overly active before you started taking medication, or they may have become inhibited once the medication was started. We all react differently when medication is taken. One thing is common with all of us—the need to maintain or get back to a natural body balance.

Oxidative stress will be significantly higher in the body of anyone diagnosed with anxiety, depression, bipolar, schizophrenia, ADHD and OCD. The brain is most susceptible to oxidative stress, and a multitude of clinical trials have shown significantly higher oxidative stress in the brain of bipolar and schizophrenic patients.   The supplements called Neuro Endure and JNK will help stop the oxidative stress before it even starts or stop the continued progress if it is already underway.

The area of nutrition is littered with confusing words and information so technical it can seem overwhelming. I have tried to simplify and distill what you need to know so you can proceed with the program while understanding the basic premise of how your body works to counteract the imbalances created by the medication.

If you wish to read more of the technical information please read the Science chapter.

Thousands of people worldwide have stood where you now stand-ready to take their lives back and free themselves from psychoactive medication and the resulting side effects. While every person is unique and life offers no guarantees, if you follow this program precisely, you should begin to feel better soon after you start.

Supplements Used in the Program

The supplements used with The Road Back Program are manufactured by Neuro Genetic Solutions (Neuro Endure Mini, JNK Capsules, Omega 3 Supreme – TG, Body Calm Daytime Relief, Body Calm Supreme With Melatonin, Body Calm Supreme Melatonin Free and Adrenalpin), Transfer Point (Beta 1-3 D Glucan) and A.C. Grace (Unique E). The chapters in this book that detail how to taper specific types of medication will list which supplements you need to use for each drug type as well as additional supplements to use for more specific withdrawal symptoms. This chapter describes all supplements that might be used in the program and gives tips on how to use each one.

Adrenalpin – (Manufactured by Neuro Genetic Solutions) Adrenalpin should be used, no matter the drug you may be taking if; when you awake in the morning you feel anxiety, the feeling tends to reduce a little as noontime approaches but then comes back again full force near noon. The anxiety feeling will usually fade again a little as the day passes and in the evening, if you are not able to be asleep by 10:30pm the anxiety feeling comes back fully and you are not able to go to sleep until after 1am.

Adrenalpin is formulated with Cordyceps (mushroom), Eleuthero, Rhodiola, Montmorency Tart Cherry and Pantothenic Acid. This formula is made to slowly reduce the feeling of daytime anxiety and help with sleep. There are more direct ways to adjust the body to eliminate the anxiety feelings but the approach is too harsh and even if you have never used a psychoactive medication those other supplements would cause you to have an increased anxiety and insomnia.

This is where even a good Naturopathic Doctor may error in the treatment of a patient on psychoactive medication. They have a formula they have used for years and it has been very effective and they feel it will be fine with most of their patients. If you are taking anti-anxiety drug this definitely is not the case. If you were prescribed an antidepressant for anxiety, it probably will cause more harm than help as well.

Slow and steady wins the race, especially with the feeling of anxiety.

You should take 2 capsules of the Adrenalpin each day with food. Take the first capsule in the morning and the second capsule about 30-minutes before the normal return of the anxiety feeling near noon. Make sure to have some food in the stomach each time you take Adrenalpin.

The Adrenalpin veggie capsules are guaranteed to dissolve within 15-minutes after swallowing.

B6, B12 and Folate – You should be able to find a B6, B12 and Folate at a local vitamin store. The supplement should be made from: Vitamin B6 (from pyridoxal 5’-phosphate) Folate (50% as folinic acid (5-formyltetrahydrofolate) and 50% as 5-methyltetrahydroflate) and B12 (as methylcobalamin).

Approximately, 30% of the population will not be able to metabolize B12 and folate with ease. If you do not use the types mentioned here, the chances of metabolism reduce further.

Taking a B6, B12 and Folate should not cause any reaction at all. Low folate levels are common with depression and we do not get enough folate in our diet, especially when 30% of us have a difficult time metabolizing it in the first place. Neuro Genetic Solutions now carries a B6 B12 and Folate as described above. Click here.

Beta 1, 3-D Glucan – This supplement is available from Transfer Point (www.transferpoint.com). The human immune system includes a substance called IL-2. Individuals with low levels of IL-2 have anxiety and problems with sleep. Stage 2 of sleep requires a sufficient level of IL-2 for a deep restful sleep.

Beta 1, 3-D Glucan has been clinically proven to not only increase levels of IL-2 in the human immune system but to also keep the IL-2 levels increased for an extended time after the product is discontinued.

If you have anxiety and or insomnia, use the JNK supplement, Body Calm Daytime Relief, Body Calm Supreme and Adrenalpin first. If these symptoms do not completely subside within 2 weeks, you may have low IL-2, and supplementing with the Beta 1, 3-D Glucan would be in order. Taking one or two of the 100 mg capsules in the morning will usually do the trick.

Tip: The Beta 1, 3-D Glucan must be taken apart from food or water and not within a half hour of consuming food or liquid. Only use enough liquid to get the Beta 1, 3-D Glucan down the throat and no more than that. The Beta 1, 3-D Glucan needs to absorb, and taking it in any other fashion will not allow assimilation.

JNK Capsules – (Manufactured by Neuro Genetic Solutions) The JNK has been reformulated to be close to the original formula from 2010. This was the most effective formula in this program, hands down. As new clinical studies were published about the individual ingredients in the formula it became apparent why it was more effective. The original JNK Capsules are back!

The ingredients in the JNK Capsule are; Milk Thistle, Selenium, N-Acetyl-Cysteine, Alpha Lipoic Acid, Biotin, Inositol, Malic Acid, Calcium as citrate malate, Alpha Ketoglutaric Acid, Vitamin K2 as menaquinone-7, and Pantothenic Acid.

Milk Thistle helps reduce the over activation of the JNK gene. The amount used in this supplement will not give much help to the liver. That is not the purpose of the Milk Thistle in this formula.

The Selenium helps reduce the over activation of the JNK gene plus it helps support normal cell health and has a specific antioxidant action.

N-Acetyl-Cysteine (NAC) creates the master antioxidant glutathione. NAC is the most heavily researched product regarding glutathione. For this reason, you will find NAC used in emergency rooms as an IV treatment and prescribed by physicians for various reasons.

NAC does help reduce the over activation of the JNK gene and works hand-in-hand with selenium, alpha lipoic acid, vitamin C and vitamin E. NAC will have an effect within the brain and liver.

Alpha Lipoic Acid helps recirculate vitamin C and vitamin E and has a distinct benefit with insulin resistance. It is normally never used as a standalone supplement but is a supporting cast member that wins best supporting actor at the Oscars each and every year.

Biotin is usually thought of for hair and nail problems. Anti-anxiety drugs deplete biotin with prolonged usage of the drug and you may have brittle hair and nails. Those are only the possible visible signs. Numbness or tingling of the extremities occurs when the drugs have depleted biotin too much. I increased the biotin in this formula to be higher than what was found in the original JNK.

Inositol is a key cell membrane component and messenger in our neuro-communication system. It signals the release of serotonin and norepinephrine. It also triggers other cellular functions, such as glucose and fat metabolism. With insulin resistance being a major underlying problem with most people taking a psychoactive drug, the more help for that area the better.

The amount of inositol in the JNK Capsule formula is not enough to stop taking inositol if you are already doing so. The amount used is just enough to be effective with the overall formula.

Malic Acid is a supplement most people have never heard of. Malic acid is used for making ATP, which is a molecule that provides energy to muscles, brain, heart and other tissues.

Calcium, as calcium citrate malate.  It is all too common for people doing this program to have the feelings associated with anxiety. Part of the physical reason can come from calcium. Calcium can excite the body rather much, to put it mildly. I have found calcium citrate does not cause this agitation but also works to calm things down. Many of us also have the genetic makeup that makes absorption of calcium difficult. I have used calcium citrate malate in the formula to give a high bioavailability of a well absorbed calcium. If you are taking a calcium supplement already, I want you to know there is 254mg of calcium citrate malate in each serving of the JNK formula. There are 3 capsules to a serving.

Alpha Ketoglutaric Acid (AKG) is another one of those supplements you probably never heard anything about. This supplement helps remove ammonia from the central nervous system.

This is an organic acid that helps metabolism of all essential amino acids and assist with the transfer of cellular energy in the citric acid cycle. The body needs AKG as a precursor to  glutamic acid, which is involved in protein synthesis and the regulation of blood glucose levels.

A buildup of ammonia in the brain, muscles and kidneys can occur with psychoactive drug usage. This is part of the reason the list of drug side effects included these areas of the body.

Vitamin K2 as menaquinone-7 is from a natural source. Vitamin K2 has a role in blood coagulation, a benefit for bone health and vascular function. This form of K2 also has the longest half-life of all K2 vitamins making it suitable for this formula.

This form of K2 has been shown to help reduce bone loss in postmenopausal women.

For those of you taking a blood thinner, the amount of K2 in each capsule is 16mcg. Please share this with your physician before taking the JNK Capsules.

Pantothenic Acid is an essential B vitamin that is needed to release energy from carbohydrates, protein and fats from food. It is also essential for the synthesis of adrenal hormones and cholesterol. This supplement is also involved in fatty acid metabolism and many of the enzyme processes of the body.

The biotin mentioned earlier, also requires pantothenic acid to be the most effective.

You will also find pantothenic acid in the Adrenalpin formula. I have kept in mind you may be taking both the Adrenalpin and the JNK Capsules and have formulated both products in such a manner so you will not have too much pantothenic acid.

The JNK Capsules are guaranteed to dissolve within 15-minutes after swallowing.

Neuro Endure and Neuro Endure Mini – Start off with the Neuro Endure Mini. The Mini is the same formula as Neuro Endure but with ¼ the strength. Most of you will only need the Neuro Endure Mini. This product was formulated to help those of you taking a timed release medication but it was found to be very effective with benzodiazepines and other drugs as well.

In testing the key ingredients of this supplement, a few things happened that were surprising. People with protracted withdrawal had symptoms leave in a manner of days. There were people that usually could not take any supplement due to adverse reactions.

Don’t be surprised if your, anxiety, insomnia, memory and concentration returns or improves. It is common for relief from body aches and pains to diminish with Neuro Endure.

Unless you are tapering from a pain medication, start with the Neuro Endure Mini. I detail how to take in the Pre-taper chapters.

The ingredients in Neuro Endure are; Acetyl-L-Carnitine, Bacopa Monnieri, L-Glutamine and N-Acetyl-Cysteine.

Acetyl-L-Carnitine reduces the over activation of the JNK gene in the brain. This is probably why this supplement has been used by physicians to help with brain and nerve function during aging. This ingredient is a metabolic source for acetylcholine, a brain neurotransmitter and with the conversion back to L-Carnitine; it helps carry fatty acids into the mitochondria of nerve, heart and muscle cells for the production of energy. Other benefits include; cell membrane stability, production of nerve growth factor and cerebral blood flow.

Bacopa Monnieri is an herb that has been used for centuries to help with mood. The amount of the herb in this formula matches the amount and strength used in the successful studies.

L-Glutamine is a primary source of energy for intestinal immune cells and a major amino acid in muscle tissue. With continual stress, the body loses the ability to manufacture enough glutamine naturally and supplementation is required.

N-Acetyl-Cysteine. Please see description of this supplement in the description of the JNK Capsules.

The Neuro Endue Mini tablets are guaranteed to dissolve within 30-minutes after swallowing.

Omega 3 Supreme TG – (Manufactured by Neuro Genetic Solutions) This omega 3 is completely a new omega 3 fish oil for The Road Back Program. With redoing the manufacturing of products used in the program, I knew the omega 3 fish oil could be upgraded to a better product. Starting from scratch, and looking at what role a fish oil has in this program; that being to assist with the “brain zaps” associated with reducing an antidepressant, a new type of fish oil was selected.

Other than the cheap, run-of-the-mill fish oil, a distillation process is used to purify the fish oil and remove heavy metals and toxins that are present in fish. All omega 3’s we recommended in the past were distilled.

During the distillation process, alcohols are used to help breakdown the fish oil and purify it. This is the time when you can increase the amount of EPA in the fish oil or the DHA fraction. If you look at the back of any fish oil label you will see EPA in milligrams, DHA stated in milligrams, as well as total milligrams of fatty acids. This is the point where nearly all fish oil processing stops due to price and you have a fish oil product called EE or ethyl esters. If the bottle of fish oil you have on your shelf does not state TG on the label, it is undoubtedly this EE form.

The EE form is not a natural form for fish oil. It is still in an altered state and not natural. Synthetic if you will.

The Omega 3 Supreme is in the TG form of fish oil. The manufacturing process for TG fish oil takes the fish oil back to the natural structure of fish oil. The human body likes natural! It knows what to do with things that are natural.

The TG stands for triglyceride. A natural omega 3 is in the triglyceride form, not the EE form.

The triglyceride in omega 3 fish oil is not the same as triglyceride as a “fat” you may want to be lowering under your doctor’s care. A completely different animal!

If you have experienced burping, the fish breathe, you have been taking the EE form of fish oil.

If you do much research on the difference between EE and TG fish oil, you will find most clinical studies have used the EE form of fish oil. That is because it is cheaper.

Once the fish oil is ready to convert back to the TG form, a choice is made on how much EPA/DHA the product will have. You will find some fish oil in TG form to have around 180mg of EPA and a low amount of DHA as well. This is great for a child as long as the total amount of fish oil is still not at 1,000mg a softgel.

Omega 3 Supreme TG has 408mg of EPA, 272mg of DHA, 70mg of other fatty acids per softgel. In the future, as new batches of the Omega 3 Supreme TG are made, the amount of EPA, DHA and total other fatty acids may go up or down slightly. The manufacturing process for fish oils is not the same as making a vitamin C where the milligram amount can be exact each time. The product is made with the same procedures, the product is then tested and measured and the exact amount must be on each label.

The cost is higher per softgel of TG omega 3 as compared to the EE form. However, the high host averages out when you compare the amount of TG softgels you will need to take is less. With TG being in a natural state, the omega 3 fish oil has over 30% higher absorption.

The next 3 supplements are where quality and price have been addressed.

Body Calm Daytime Relief – (Manufactured by Neuro Genetic Solutions)

Body Calm Daytime Relief is formulated to be used during the daytime to help with relief from anxiety. If you are responding quite well to this supplement during the daytime you may want to try it at bedtime as well for sleep.

The Montmorency tart cherry is without binders or fillers from the supplier, passion flower is pure and at a good strength but not too much to make you drowsy. .

I was the first to recommend the Montmorency cherry for anxiety and sleep back in 2004. You may find other cherry supplements now recommended for these symptoms and if they did not work for you don’t think this supplement will not. Using a pure cherry powder, including the skin, without binders makes a huge difference in this product.

Using this supplement is different than most other supplements you might have used for anxiety or sleep. They do not make you drowsy or sleepy.

The Body Calm Daytime Relief works well when taken together with the Adrenalpin. Getting relief from the daytime feelings of anxiety is essential for a productive day and believe me; a day filled with the feeling of anxiety does get in the way of your sleep. I am probably preaching to the choir here but if you also have a difficult time with sleep, what you do or do not do in the daytime will directly affect how well and how easy you can go to sleep.

The veggie capsules used with Body Calm Daytime Relief are guaranteed to dissolve within 15-minutes after swallowing.

Body Calm Supreme Melatonin Free – (Manufactured by Neuro Genetic Solutions) When you take this supplement 15-minutes before bedtime the capsule will dissolve right as you go to bed. Don’t expect to feel sleepy suddenly. Close your eyes and start going to sleep and don’t be surprised if you just awake the next morning.

Body Calm Supreme Melatonin Free includes a blend of Montmorency tart cherry, passion flower, L-Theanine and GABA. If you compare the formula of Body Calm Daytime Relief and Body Calm Supreme Melatonin Free you will notice the exact same formula. However, the amount of each ingredient has been changed to help guide you through the switchover from the Body Calm Daytime Relief to sleep, without jarring your system. The amount of GABA used in this formula is very low.

One to two capsules 15-minutes before bedtime.

The veggie capsules used with Body Calm Supreme Melatonin Free are guaranteed to dissolve within 15-minutes after swallowing.

Body Calm Supreme With Melatonin – (Manufactured by Neuro Genetic Solutions) This formula is the exact same as the Body Calm Supreme Melatonin Free except for the addition of vitamin B1 as Benfotiamine and melatonin.

Vitamin B1 as Benfotiamine was used because I wanted a B1 that would cross the blood-brain-barrier. Melatonin can cause some people to have vivid nightmares or vivid dreams and B1 has been shown to help.

Take 1 to 2 capsules 15-minutes before bedtime.

The capsule is guaranteed to dissolve within 15-minutes after swallowing.

Unique E – Omega 3 fish oil requires vitamin E for absorption. If you take any omega 3 fish oil daily you will become deficient in vitamin E in time. I have recommended the Unique E made by A.C. Grace Company for years. A.C. Grace has been making vitamin E for over 50-years and their blend of mixed vitamin E is unique, as their name suggest. It is a natural blend of the parts that make up vitamin E. Neuro Genetic Solutions will probably carry the Unique E so you do not need to shop at multiple web sites. If you would prefer to purchase directly from A.C. Grace, their web site is www.acgrace.com.

A recap on where the supplements are available.

Neuro Genetic Solutions – Adrenalpin, JNK Capsules, Neuro Endure, Neuro Endure Mini, Omega 3 Supreme TG, Body Calm Daytime Relief, Body Calm Supreme Melatonin Free, Body Calm Supreme With Melatonin

www.shop.neurogeneticsolutions.com

Neuro Genetic Solutions is based in the United States and has distributors in Europe, Australia, and Canada and very soon in Hong Kong. Go to www.shop.neurogeneticsolutions.com for international distributor web site information.

Beta 1-3D Glucan – Is available at www.transferpoint.com